Menu
NEWEST
Hydrate Deeply, Renew Completely
Before & After
What Should You Expect From Our Treatment?
Before
After
Dull, dehydrated complexion
Deeply hydrated, luminous skin
Visible fine lines and loss of elasticity
Firmer appearance with reduced lines
Uneven skin tone and texture
Even tone and refined texture
Slow post-procedure recovery
Accelerated healing and regeneration
Skin lacking youthful glow
Long-lasting radiant glow
Steps
Your NEWEST Treatment Journey: What to Expect
Step 1: Consultation and Assessment
Initial Consultation: Discuss your concerns and goals with our practitioner.
Skin Analysis: Evaluate your skin’s condition to tailor the treatment.Step 2: Pre-Treatment Preparation
Cleanse and Prepare: Thoroughly cleanse the treatment area.
Numbing Cream (Optional): Apply numbing cream if needed to minimize discomfort.Step 3: The Treatment Process
A quick, 15-minute micro-injection protocol: the practitioner administers 0.2 ml per facial zone, placing the hyaluronic-acid–polynucleotide complex into the superficial dermis with a fine needle to hydrate, regenerate fibroblasts, and “prime” skin for enhanced absorption of subsequent treatments .
Step 4: Post-Treatment Care
Immediate Aftercare: Expect mild redness or swelling, which usually subsides quickly.
Avoid Sun Exposure: Protect your skin from the sun and use sunscreen.
Follow-Up Instructions: Follow detailed aftercare instructions for best results.Step 5: Results and Follow-Up
Gradual Improvement: Notice improved hydration, texture, and appearance over weeks.
Follow-Up Consultation: Assess results and discuss further treatments if needed.
Ready to Book?
Are You Looking For Microneedling Treatment?
Already a Customer?
Welcome back! Schedule your next treatment or explore new options with us.
New to XO Skin Clinic?
Discover advanced aesthetic treatments designed to enhance your natural beauty.
Pricing
Transparent Pricing: Your Path to Affordable Aesthetics
NEWEST (10mg/1ml) by MASTELLI
NEWEST is a dual-action injectable combining hyaluronic acid and polynucleotides to hydrate, regenerate and rejuvenate skin in one treatment.
FAQS
Do you have any questions in mind?
NEWEST is a sterile injectable combining 10 mg/ml polynucleotides with 10 mg/ml hyaluronic acid and protective mannitol, designed to hydrate, regenerate and improve skin quality in one session.
Polynucleotides stimulate fibroblast activity and collagen synthesis while hyaluronic acid delivers immediate hydration; mannitol acts as a free-radical scavenger, prolonging HA stability by 34 % .
Clients with mature, dehydrated or sun-damaged skin seeking smoother texture, improved elasticity and long-lasting glow.
Yes. The formulation is biocompatible and fully absorbable, with minimal risk of immunological reaction due to its salmon-derived DNA composition .
Approximately 15 minutes, including consultation and gentle post-treatment massage.
Hydration is visible within 48 hours; collagen remodelling and textural improvements develop over 4–6 weeks.
Clinical data show sustained improvement for 6–9 months, depending on age, lifestyle and skin condition .
Absolutely—it “primes” the skin, enhancing the efficacy of subsequent lasers, peels or microneedling.
Mild erythema or swelling may occur for 24–48 hours; serious adverse events are rare when administered by trained professionals.
One syringe (2 ml) per session, repeated 2–3 times at 4-week intervals for optimal bio-regeneration, followed by single maintenance sessions every 6–9 months.
